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Green tea and body weight loss: recent studies

Green tea and body weight loss: recent studies

Over the past three decades, green tea, made from the leaves of the Camellia sinensis plant, has been studied for its beneficial effects including: anti-inflammatory, neuroprotective against neurological disorders, anti-cancer ("green tea catechins are widely described as effective in the prevention of lung, breast, esophageal, stomach, liver and prostate cancer "..." their beneficial effects may support the standard anticancer approach", source: "Beneficial Properties of Green Tea Catechins", 2020, PubMed e International journal of molecular Science Int J Mol Sci.2020).

Green tea has also been shown to reduce body weight, relieve metabolic syndrome, and prevent type 2 diabetes and cardiovascular disease in animal models and humans. However, not all drinks or green tea extracts seem to be effective on body weight: only those rich in catechins, or at least in which the catechins contained are higher than the minimum dosage of 150 mg/day (source: Green tea beverages enriched with catechins with a galloyl moiety reduce body fat in moderately obese adults: a randomized double-blind placebo-controlled trial, 2016, PbMed).

Green tea: active ingredients

Green tea leaves essentially contain catechins, theanine, caffeine. Green tea catechins are flavonoids (polyphenols with a skeleton of 15 C atoms), belonging to the class of flavans, group of flavanols. The group of non-fermented green tea catechin derivatives includes: (+) - catechin, gallocatechin, epicatechin, epigallocatechin (EGC), epicatechin gallate (ECG), epigallocatechin gallate (EGCG). The latter of these exhibits the most potent anti-inflammatory and anticancer potential.

Recent scientific research indicates that the number of hydroxyl groups and the presence of characteristic structural groups have an important impact on the antioxidant activity of catechins. Catechins show the strong property of neutralizing reactive oxygen and nitrogen species.

As for the metabolism, the catechins:

- inhibit the synthase of fatty acids (FAS kinase PI3K (phosphatidylinositol kinase 3), in particular gallocatechins; Akt. Hossain et al., 2016;

- improve energy expenditure with a thermogenic effect; Türközü and Tek, 2017;

- lower insulin resistance and modulate beta oxidation which transforms fatty acids in adipose tissue into energy; Sae-Tan et al., 2011.

Green tea catechins and body weight

Green tea from Camellia sinensis has been shown, in adequate doses of catechins, to reduce body weight, alleviate metabolic syndrome and prevent diabetes ("Epigallocatechin gallate improves insulin resistance in HepG2 cells through alleviating inflammation and lipotoxicity", Diabetes Rec Clin Pract . 2018 Aug; Qiao Zhang 1, Hang Yuan 1, Cong Zhang 1, Yue Guan 1, Yuqing Wu 1, Fan Ling 1, Yucun Niu 2, Ying Li 3) and cardiovascular disease in animal models and humans. Despite numerous studies, the fundamental mechanisms of these actions still remain unclear. From a literature review conducted by authors Yang CS, Zhang J, Zhang L, Huang J, Wang Y. in "Mechanisms of body weight reduction and metabolic syndrome alleviation by tea" (PubMed), the two main mechanisms proposed are:

(i) decreased absorption of lipids and proteins by the constituents of tea in the intestine, thus reducing caloric intake; is

(ii) activation of AMP-activated protein kinase by tea polyphenols which are bioavailable in the liver, skeletal muscle and adipose tissue. The relative importance of these two mechanisms depends on the types of tea and diet consumed by the individuals. Activated AMP-activated protein kinase would decrease gluconeogenesis and fatty acid synthesis and increase catabolism, leading to reduced body weight and attenuation of the metabolic syndrome.

   

Already in 2007, in a study published in PubMed and entitled "Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea": there was a discussion about some substances including caffeine, ephedrine, capsaicin and green tea, as strategies for weight loss and weight maintenance, as they can increase energy expenditure and have been proposed to counteract the decrease in metabolic rate that is present during weight loss. The study found that: "a combination of caffeine and ephedrine has been shown to be effective in long-term weight management, however, the negative effects of ephedrine prevent the feasibility of this approach; capsaicin has been shown to be effective, but when used clinically it requires strong adherence to a certain dosage, which has not yet proved feasible; positive effects on weight management have been demonstrated using green tea blends. Green tea, containing both tea catechins and caffeine , can act through the inhibition of catechol O-methyl-transferase and the inhibition of phosphodiesterase. Here, the mechanisms can also work synergistically. Furthermore: tea catechins have antiangiogenic properties that can prevent the development of overweight and obesity; Sympathetic nervous system is involved in the regulation of lipolysis and the sympathetic innervation of white adipose tissue it can play an important role in regulating total body fat in general. "

As also reported in an article published in PubMed "Nutraceuticals for body-weight management: The role of green tea catechins, 2016" Green tea catechins mixed with caffeine have been proposed as adjuvants to maintain or increase energy expenditure and to increase 'oxidation of fats, in the context of the prevention and treatment of obesity: they seem to counteract the decrease in the metabolic rate that occurs during weight loss. Their effects are of particular importance also when maintaining weight after weight loss. In conclusion, a blend of green tea catechins and caffeine has a beneficial effect on body weight management, in particular through sustained energy expenditure, fat oxidation and lean body mass maintenance, after induced body weight loss. 

Natural fat burner: here's what Erboristeriacomo.it recommends

You can find on erboristeriacomo.it our natural fat burner, BruciaFat, which is based on an exclusive synergized complex based on cassia noname aerial part dry extract tit. 8% in total catechins, Tamarind fruit dry extract tit. 5% tartaric acid and green tea from Camellia Sinensis leaves dry extract tit. 40% in epigallo catechin gallate. Cassia nomame assists the metabolism of triglycerides and cholesterol, green tea extract is useful for the balance of body weight, tamarind for the regularity of intestinal transit and it is recommended to take one tablet before lunch and one before dinner. It is obvious, however, but it should be pointed out, that supplements are not intended as a substitute for a varied and balanced diet and a healthy lifestyle. BruciaFat can also be associated, to exploit its synergism, with: strong draining DrenaSel forte or bruciadren fast (for a "shock" drainage program, with the aim of eliminating excess fluids), with FameSel (a disappetive that contains griffonia, gymnema that promotes carbohydrate metabolism, banaba and cinnamon) or DrenaSel Active, to reduce fat mass.

The Specchiasol company also wanted to exploit the properties of green tea, inserting a soft extract in the Primum dren stick, and a phytosomal extract tit. 19% in catechins calculated as EGCG in Pesobalance, in which it was decided to mix it with: green coffee tit. 45% in chlorogenic acid, capsicum tit.2% in capsaicinoids and black pepper tit. 95% in piperine.

Dr. Laura Comollo

Visit our herbal department for any clarification or for more information.

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